Noteworty news from medtech start-ups. In this issue: NOTES companies promise the least invasive surgery, with brief profiles of Apollo Endosurgery, Minos Medical and Cardiorobotics. (Adapted from "NOTES Companies Sing an Upbeat Tune," START-UP, December 2007.)

Brief summaries of recent product and company developments in the device industry, including: developments in continuous glucose monitoring, new liability conerns for device companies, medtech acquisitions in 2007, and the 2008 IPO market.

A roundup of recent medtech strategic alliances, mergers & acquisitions and financings.

The FDA Amendments Act of 2007, siged into law in September, proposes many changes designed to improve drug and device safety and efficiency as well as make the approval process more transparent to the public.