Gene link to breast cancer history questioned
This article was originally published in Clinica
Executive Summary
The likelihood of a woman with a family history of breast cancer carrying a germ line mutation in BRCA1 or BRCA2 is not as great as previously thought, according to Australian researchers. If they are right, mutation testing for BRCA1 and BRCA2 in "high-risk" families is unlikely to identify more than a small proportion of all the mutation carriers in the population.