US team develops prognostic gene chip for neuroblastoma:
This article was originally published in Clinica
Executive Summary
US researchers have developed a DNA chip that could help predict outcomes for infants with neuroblastoma, a common form of cancer in children less than 10 years of age. The chip can be configured to identify selected genetic abnormalities and deletions in isolated regions of chromosome 11, which is believed to allow aggressive neuroblastoma to take hold. Investigators from The Children's Hospital of Philadelphia and Thomas Jefferson University said that the chip could also be modified to help identify other forms of cancer. Their proof-of-principle study featured in the August edition of Genome Research. The team is currently seeking industry support to help improve the technology.