Derived from Strategic Transactions, Informa's premium source for tracking life-sciences deals, the bimonthly Pacts In Medtech feature highlights notable technology alliances, research and development partnerships and commercial collaborations. This edition covers industry pacts that were signed in September and October 2019.

The 20 non-US medical device approvals in January, including eight in in vitro diagnostics, four in orthopedics, and three in cardiovascular devices. Big medtech players Medtronic and Abbott, accompanied by much smaller Swiss IVD firm Abionic, led the charge and bagged more OUS approvals than most.

Advanced Cooling Therapy Inc. has developed a novel device that control's a patient’s entire body temperature by either heating or cooling blood surrounding the esophagus.

In this month's issue of Start-Up, we profile 4Tech, Advanced Cooling Therapy, Enumeral Biomedical Holdings, MiNDERA, PeptiMimesis and Synchron.