Biorthex Inc.

Building a pipeline in spinal nonfusion 505 Park Avenue 14th Floor New York, NY 10022 Phone: (212) 583-9700 Fax: (646) 349-1173 Web Site: www.paradigmspine.com Contact: Marc R. Viscogliosi, Chairman

A fragmented small bone and joint market coalesces into the next big opportunity in orthopedics 505 Park Avenue, 14th Floor New York, NY 10022 Phone: (212) 583-0370 Fax: (212) 826-9509 Web Site: www.t

First stop: minimally invasive annulus repair ES&T Building311 Ferst Drive NW Atlanta, GA 30332 Phone: (404) 385-4065 Fax: (404) 385-4638 E-Mail: steve.kennedy@orthonics.com Contact: Stephen J. Kenn

Clinical trials strategies, particularly in the medical device industry, can confer an important competitive advantage to a company—or present a stumbling block that costs time, money, and markets. Th