AstraZeneca terminates deal with Biota after trial failure

AstraZeneca is to terminate its antiviral licensing agreement with Biota after the Australian company's BTA9881 failed to meet safety requirements in a Phase Ia clinical trial for respiratory synctial virus (RSV).

AstraZeneca is to terminate its antiviral licensing agreement with Biota after the Australian company's BTA9881 failed to meet safety requirements in a Phase Ia clinical trial for respiratory synctial virus (RSV).

BTA9881 exhibited nearly 100% oral bioavailability in humans and a safety profile in humans comparable with placebo at the doses...

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