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TCT 2018: New ABSORB Trial Data Fails To Impress

 
• By Marion Webb

Abbott's defunct Absorb BVS stent's efficacy is noninferior to that of the Xience metallic everolimus-eluting stent, new data presented at the Transcatheter Cardiovascular Therapeutics (TCT) conference in San Diego show. But the risk of thrombotic events was still higher with Absorb. This prompted a discussion among panelists whether bioresorbable stents should still be investigated, given the availability of newer-generation drug-eluting stents, which have shown to be safer.

San Diego convention center as seen from the Embarcadero South.
The 2018 TCT Conference was held in San Diego, Sept. 21-25. • Source: shutterstock.com

One-month and one-year results from the ABSORB IV trial did not show a significant difference in efficacy between Abbott Vascular's now-defunct Absorb BVS bioresorbable stent and Abbott's Xience metallic everolimus-eluting stent, but the 30-day and one-year rates of myocardial infarction, device thrombosis, and target-lesion revascularization were worse with Absorb.

Gregg Stone, professor at Columbia University Medical Center, presented findings of the pooled meta-analysis of four randomized trials during a late-breaking session at the Transcatheter Cardiovascular Therapeutics (TCT) on Sept....

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