SetPoint Turns Up The Heat On Rheumatoid Arthritis Program

Having raised $30m in its latest financing round, SetPoint Medical is now focusing squarely on its rheumatoid arthritis program. The neuromodulation company, which counts Medtronic, Boston Scientific and GSK among its investors, is aiming to kick off Phase II trials before the end of the year, using a commercial-ready version of its implantable vagal nerve stimulation technology.

Neuromodulation
Setpoint Medical seeks to introduce bioelectric medicines for inflammatory diseases • Source: Shutterstock

SetPoint Medical Corp. is sharpening its focus on the rheumatoid arthritis therapy market, currently dominated by biopharmaceuticals, by channeling a good part of the $30m series D financing it recently raised into a multi-center Phase II clinical trial of its vagus nerve stimulation system.

The California company's technology is a rechargeable implant the size of a vitamin pill placed on the left side of the vagus nerve. It is programmed to stimulate specific fibers within the nerve, for a few minutes once a day, which then activates the body's natural inflammatory reflex

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