Not Too ATTRACTive Data For Catheter Thrombolysis In Combatting Post-Thrombotic Syndrome

Randomized trial results show pharmacomechanical, catheter-directed thrombolysis does not reduce the development of post-thrombotic syndrome in patients treated for deep-vein thrombosis. The study’s investigator suggests limiting the procedure to treatment of large iliofemoral blood clots causing major symptoms in patients who are at low risk of bleeding.

blood clot
• Source: shutterstock.com

Two-year results of the ATTRACT trial show that pharmacomechanical catheter-directed thrombolysis (PCDT) to treat deep-vein thrombosis does not reduce the patients’ chances of developing post-thrombotic syndrome, but does increase their risk of major bleeding compared anticoagulation drug therapy alone.

“[ATTRACT] provides the first high quality data on PCDT and will enable doctors to target its use to patients who may benefit, prevent costly and unnecessary procedures in...

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