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CircuLite: Partial Support Enables Patient Management

This article was originally published in Start Up

Executive Summary

There is a large group of chronic heart failure patients--more than two million of them worldwide-who are resistant to or have failed drugs or devices, but aren't yet eligible for the cardiac assist devices approved for end-stage patients. Back in 2006, when START-UP first spoke with CircuLite, the company was after those patients, with a small pump that, in providing partial circulatory support, would be in an entirely different category than LVADs. Today, on only a bit more than $36 million in funding, CircuLite has developed the Synergy Pocket Micro-pump, a tiny pump designed to provide partial assist to the heart. Synergy has completed its first-in-man study, and is nearing completion of its European clinical trial supporting a CE mark.


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