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Cardiovascular Devices

For all the attention given to cardiovascular disease, it still remains an unmet medical need. Now, a new crop of start-ups tries to improve the mortality rates for heart disease.

Of all the segments of the medical device industry, the one that most rewards technological innovation, in terms of pricing and profitability as well as company valuations, is devices that treat or manage cardiovascular disease (CVD). CV start-ups continue to attract venture funding at rates far exceeding other device segments. Similarly, it's no surprise that most of the major device firms that emerged as Wall Street darlings during the 1990s—companies like Guidant Corp. , Medtronic Inc. , and Boston Scientific Corp. —built their businesses, either wholly or in substantial part, on cardiovascular plays.

Yet for all the attention paid to CVD, there remain pockets of huge unmet medical need. One in five men can expect to develop a major CVD before age 60;...

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