Stroke care will never be the same. The important findings from the MR CLEAN, ESCAPE, EXTEND-IA, SWIFT PRIME and REVASCAT trials, all recently published in the New England Journal of Medicine, along with new guidelines from the American Heart Association and the Society of NeuroInterventional Surgery, have established mechanical thrombectomy as a new mainstay of therapy for acute ischemic stroke (AIS), and ushered in a new era in stroke treatment. For the last 20 years, the gold standard treatment for AIS has been intravenous tissue plasminogen activator (IV tPA), a clot-busting drug that must be given within 4.5 hours after stroke onset in order to be effective. However, IV tPA has generally not been effective in dissolving clots in patients with large anterior strokes, the most deadly and disabling type, and these patients have had few or no treatment options – until now. (See Also see "Stroke Devices: Hope Amid Headwinds" - Medtech Insight, 27 September, 2013..)
Intracranial mechanical thrombectomy is an endovascular procedure in which physicians thread a catheter through the femoral artery to the site of the clot in the brain, where they use a...