Fractional flow reserve (FFR), a functional measurement of arterial blood flow typically performed during coronary angiography, is slowly beginning to gain traction among US interventional cardiologists seeking additional surety that a patient’s blocked coronary artery needs to be stented. Although FFR is currently used in fewer than 10% of US stenting cases, that number is expected to rise substantially in the coming years as intense cost-control measures come into play and physicians face increasing pressures to reduce unnecessary stenting procedures. And now, what might be described as a second generation of FFR is emerging that has the potential to leap-frog over existing FFR technology. This wave of next-generation technology includes noninvasive computed tomography (CT)-based FFR, developed by start-up HeartFlow Inc., as well as a new adenosine-free FFR technology under development by Volcano Corp. in collaboration with researchers from Imperial College London.
The basic goals of these new approaches are to make FFR measurements more reliable, more versatile, and/or easier to perform,...