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Noteworthy news from medtech start-ups, including Vasorum's redefinition of vascular closure, Novian Health's energy-based breast tumor ablation, Tissue Genetics' molecular diagnostics for cancer, and Aponos Medical's wound closure for NOTES.

The use of arterial puncture closure devices has become an increasingly common practice in hospitals as financial pressure is pushing facilities to release patients as soon as possible following cardiac catheterization. About 4.3 million catheter-based procedures involving arterial punctures were performed in the US in 2006, and an additional 4.3 took place in Europe. The market is expected to increase at a 7.5% compounded annual growth rate (CAGR) and by 2010 reach more than 10 million procedures combined in the US and Europe. Meanwhile, global sales of arterial puncture closure devices reached over $600 million in 2006 and are forecast to exceed $1 billion by 2010.

Two large manufacturers—St. Jude Medical Inc. and Abbott Laboratories Inc.—dominate in this market, but a young company, Vasorum Ltd., is preparing to challenge the established firms with a new device...

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